Boreanaz's first paid acting appearance was a 1993 guest spot on the sitcom Married... with Children, as Kelly's two-timing biker boyfriend, who gets pummeled by her father, Al. He was cast in Buffy the Vampire Slayer after being suggested for the role to director of casting Marcia Shulman by one of Boreanaz's neighbors and future manager, after walking his dog past their house. The show became enormously successful and Boreanaz starred in the spin-off series Angel. He appeared on Buffy from 1997 to 1999, at which point he began starring in Angel, which ran until 2004, with some guest appearances on Buffy before his departure.
He has been married to actress and Playmate Jaime Bergman since November 24, 2001. In 2004, Boreanaz underwent reconstructive surgery on the anterior cruciate ligament of his left knee, a result of a running injury he suffered in high school that was not fully corrected at that time. His recovery did not prevent Angel production from continuing, but did limit his mobility and physical activities in several episodes, including his directorial debut "Soul Purpose."
Boreanaz's only starring role in a major theatrical film was in 2001's slasher-horror film Valentine. In 2002, he had a supporting role in a Lifetime television movie titled I'm with Lucy. In 2003, he appeared in the music video for singer Dido's hit single "White Flag," and was the voice of Leon (Squall Leonhart) in the video game Kingdom Hearts, but he did not reprise his role in the sequel. In 2005, Boreanaz began starring opposite Emily Deschanel on the prime time television series Bones. He also appeared in These Girls, a 2006 Canadian film in which he played a biker. He has also starred in the independent films Mr. Fix It and Suffering Man's Charity (released on DVD as Ghost Writer), as well as the direct-to-DVD sequel The Crow: Wicked Prayer. In 2006, he starred in another DVD release, The Hard Easy. In that same year, he also voiced Hal Jordan in the direct to video DC Comics animated feature Justice League: The New Frontier.
As well as being a producer on Bones since its third season, Boreanaz also directed a number of episodes, including "The Bones that Foam," "The Parts in the Sum of the Whole," "The Bullet in the Brain," and "The Blackout in the Blizzard." It has also since been reported by Hart Hanson, the creator of Bones, that Boreanaz has directed and starred in the series' 100th episode airing in the fifth season. BuddyTV ranked him #13 on its "TV's 100 Sexiest Men of 2010" list and #18 in 2011.
In the 2011 movie The Mighty Macs, Boreanaz played the role of Ed Rush, NBA referee and husband of Immaculata basketball coach Cathy Rush. David completed his role as Det. Les Scanlon in the fantasy drama 2012 Officer Down. In 2017, Boreanaz joined the regular cast as Jason in the CBS military drama series SEAL Team.
Boreanaz has appeared in a total of 167 episodes: 57 in Buffy the Vampire Slayer and all 110 of Angel:
- "Welcome to the Hellmouth"
- "The Harvest"
- "Teacher's Pet"
- "Never Kill a Boy on the First Date"
- "Out of Mind, Out of Sight"
- "Prophecy Girl"
- Buffy the Vampire Slayer season 2 (Credited but does not appear in "Inca Mummy Girl")
- Buffy the Vampire Slayer season 3
- "The Freshman" (Uncredited)
- Angel season 1
- "The Yoko Factor"
- Angel season 2
- "Fool for Love"
- Angel season 3
- Angel season 4
- "End of Days"
- Angel season 5
Boreanaz directed the episode "Soul Purpose."
Boreanaz voiced Angel in the Buffy the Vampire Slayer 2003 video game adaptation for Xbox.
Boreanaz appeared in the following Angel featurettes:
- "Season 1 Overview"
- "Introducing Angel"
- "I'm Cordelia!"
- "Season 2 Overview"
- "The Make-Up of Angel"
- "Action! The Stunts of Angel"
- "Season 3 Overview"
- "Darla: Deliver Us From Evil"
- "From Page to Screen"
- "Season 4 Overview"
- "The Final Season"
- Audio commentary for "Soul Purpose"
- "Hey Kids! It's Smile Time"
- "Choreography of a Stunt"
- "Angel 100"
Behind the scenes for Buffy the Vampire Slayer and Angel.
- David Boreanaz on Wikipedia
- Christopher Golden. 20 Years of Slaying: The Watcher's Guide. Simon Pulse, October 2017.
- "Taking Wing". PEOPLE.com, December 10, 2001.
- "David Boreanaz: TV's most famous vampire is back—only this time he's taking a bite out of crime as an FBI agent in Fox's hot new show Bones. Check out our exclusive MF interview". Men's Fitness, September 2005. Archived from the original on May 6, 2009.
- David Fury. Angel Season Five on DVD; DVD commentaries for the episode "You're Welcome" [DVD]. 20th Century Fox, February 15, 2005.