As someone who hasn't gotten yet to reading the follow up comics I'd say take inspiration from them cause I guess in that they actually continue the cliffhanger from the angel finale, I wouldn't mind seeing that in live action.
Im not saying I want this to be the villain at least main villain but I don't mind the idea of bringing back the first evil to finally stop it once and for all so it cant try to bring another apocalypse.
Just the fanboy in me says bring back Drusilla cause Juliet landau who plays her was very kind to me on social media multiple times so yeah bring her back and maybe make her a good person this time idk.